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. 2012 Apr;190(4):1461–1476. doi: 10.1534/genetics.111.135541

Table 1. Simulation results and analytical predictions for viability after 50 generations of no management or equal family contribution.

Equal family contributions
No management:Mean viability
Mean viability
Case λ E(s) Shape E(h) δ N δ* Neutral IPb FMc Sd Neutral IPb FMc Sd ΔLs at t = 50a
a 2 0.01 0.07 0.35 3.75 25 0.55 0.09 0.25 0.28 0.24 0.09 0.33 0.38 0.38 0.003
b 1 0.025 0.25 0.35 3.82 25 0.53 0.08 0.32 0.35 0.34 0.09 0.37 0.38 0.40 0.079
c 0.5 0.05 1.0 0.35 1.65 25 0.29 0.35 0.56 0.57 0.51 0.35 0.62 0.52 0.52 0.215
d 0.1 0.10 0.5 0.35 0.74 25 0.10 0.64 0.88 0.88 0.88 0.62 0.89 0.85 0.86 0.066
e 0.03 0.264 2.3 0.35 0.19 25 0.04 0.89 0.98 0.98 0.98 0.89 0.97 0.95 0.95 0.024 (0.092)
h 0.03 0.264 2.3 0.20 0.51 25 0.08 0.74 0.96 0.97 0.97 0.72 0.95 0.93 0.95 0.024 (0.042)
i 0.5 0.05 1.0 0.35 1.66 100 0.62 0.69 0.76 0.83 0.84 0.69 0.84 0.67 0.69 0.255
j 0.03 0.264 2.3 0.20 0.50 100 0.14 0.90 0.96 0.98 0.98 0.89 0.97 0.95 0.96 0.024 (0.050)
Mean squared error for FM 0.00070 0.00017
Mean squared error for García-Dorado 2008 “full” predictions 0.00089 0.00079

Results are given for different cases, each characterized by the effective sizes after population shrinkage (N), the deleterious mutation rate (λ), the mean and shape parameter of the gamma distribution for s (E(s) and “Shape”) and the average dominance coefficient (E(h). δ and δ* are, respectively, the inbreeding depression rates at the ancestral an the new MSD balance under no management.

a

Increase of the relative expressed segregating load ascribed to EFC. Regular font: bounded prediction computed from Equation B2; Italic font: unbounded prediction computed from Equation B1a, given only when larger than the MS bound.

b

Inbreeding-Purge predictions.

c

Full-Model predictions.

d

Simulation results published by Fernández and Caballero (2001).