Table 1.
Measures at Baseline by Reflux Esophagitis, Normal Histology, and Control Group
| Reflux Esophagitis (n=50) |
Normal Histology (n=53) |
Controls (n=142) |
p-value GER vs. FD |
p-value GER vs. Control |
p-value FD vs. Control |
|
|---|---|---|---|---|---|---|
| Mean Age in Years mean ± SD |
11.58 ± 2.43 | 11.98 ± 2.55 | 10.96 ± 2.11 | NS | NS | <0.05 |
| Gender (% female) | 48 % (24/50) |
68% (36/53) |
56% (79/142) |
NA | NA | NA |
| Race (% white) | 94% (47/50) |
89% (47/53) |
96% (135/141) |
NA | NA | NA |
| Intact Family (% live both parents) |
60% (30/50) |
62% (33/53) |
46% (65/142) |
NA | NA | NA |
| Dyspeptic Severity (CSI) mean ± SD |
9.96 ± 4.79 | 9.42 ± 4.58 | 2.67 ± 3.72 | NS | <0.001 | <0.001 |
| Abdominal Pain Severity (API); mean ± SD |
2.16 ± 0.81 | 2.08 ± 0.83 | 0.65 ± 0.79 | NS | <0.001 | <0.001 |
| Depressive Score (CDI) mean ± SD |
8.76 ± 5.89 | 8.77 ± 7.71 | NA | NS | NA | NA |
| Functional Disability (FDI)a; mean ± SD |
11.05 ± 8.80 | 9.15 ± 8.22 | 4.26 ± 5.58 | NS | <0.001 | <0.001 |
a
Child Report FDI not available for all subjects (Reflux Esophagitis=39, Normal Histology=33, Control=82)
Note: CSI= Children's Somatization Inventory; API= Abdominal Pain Index; CDI= Children's Depression Inventory; FDI= Functional Disability Inventory; NS= not significant; NA= not applicable