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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Bioanalysis. 2012 Jan;4(2):157–166. doi: 10.4155/bio.11.303

Figure 2. Calibration standard curves with and without deuterated internal standard.

Figure 2

(A) No IS, calibration curve fitted with 1/× weighted quadratic regression. (B) Deuterated LF (LF-D9) as the IS, calibration curve fitted with 1/× weighted linear regression. (C) IS signal intensity at the different calibrator concentrations. The LF-D9 signal decreased at higher LF concentration, indicating signal saturation at the high end of calibrators. The ratio of LF/LF-D9 still increased in a linear mode.

LF: Lumefantrine; IS: Internal standard.