Table.
Mice | Diet | Total Cholesterol, mg/100 mL Plasma | HDL Cholesterol, mg/100 mL Plasma |
---|---|---|---|
C57BL6/SW129 | Control | 83.5±6.0 | 70.7±5.2 |
Probucol | 14.7±3.1 | 11.2±2.8 | |
SR-BI KO | Control | 213.3±15.8 | 167.8±8.6 |
Probucol | 72.2±12.2 | 62.8±11.5 | |
DBA/J | Control | 69.0±6.0 | 47.0±4.4 |
Probucol | 11.0±2.4 | 5.3±1.0 | |
ABCA1 KO | Control | 9.4±2.2 | 1.2±0.4 |
Probucol | 8.0±2.0 | 1.5±0.5 |
HDL indicates high-density lipoprotein; SR-BI, scavenger receptor class B type I; KO, knockout; and ABCAI, ATP-binding cassette transporter 1. Values are mean±SD. In each group, n=6 samples were determined. See Methods for details on diets and lipid analysis.