Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
IC50 values of FdUMP[10], 5-FU, Dox, and Ara-C
| Chemotherapy | MFL2 | MR2 | M1 |
|---|---|---|---|
| FdUMP[10], pM | 131.4 (108.3-159.3) | 124.2 (97.9-157.7) | 123.8 (111.5-137.6) |
| 5-FU, nM | 292.3 (251.8-339.4) | 214.0 (178.9-255.9) | ND |
| Dox, nM | 24.6 (15.9-38.1) | 11.4 (7.2-18.2) | 3.7 (3.4-4.2) |
| Ara-C, nM | 54.4 (58.4-182.7) | 71.8 (75.9-166.5) | 46.8 (43.5-50.4) |
Values are mean (95% CI).
MFL2 indicates MLL-ENL + Flt3 ITD; MR2, MLL-ENL + NRasG12D; M1, MLL-ENL alone; and ND, not done.
