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The Journal of General Physiology logoLink to The Journal of General Physiology
. 1966 Jul 1;49(6):1177-1198. doi: 10.1085/jgp.0491177

In Vivo Studies on Fast and Slow Muscle Fibers in Cat Extraocular Muscles

PAUL BACH-y-RITA 1, FUMIO ITO 1
PMCID: PMC3328321  PMID: 5924106

Abstract

In anesthetized in vivo preparations, responses of two types of extraocular muscle fibers have been studied. The small, multiply innervated slow fibers have been shown to be capable of producing propagated impulses, and thus have been labeled slow multi-innervated twitch fibers. Fast and slow multi-innervated twitch fibers are distinguished by impulse conduction velocities, by ranges of membrane potentials, by amplitudes and frequencies of the miniature end plate potentials, by responses to the intravenous administration of succinylcholine, by the frequency of stimulation required for fused tetanus, and by the velocities of conduction of the nerve fibers innervating each of the muscle fiber types.

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