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. 2005 Jul-Sep;25(1):28–33.

HEPATOPROTECTIVE EFFECT OF A POLYHERBAL FORMULATION (AYUSH-LIV.04) AGAINST ETHANOL AND CCl4 INDUCED LIVER DAMAGE IN RATS

K Narayanasamy δ, V Selvi
PMCID: PMC3330893  PMID: 22557185

Abstract

A polyherbal formulation was evaluated for its hepatoprotective activity against ethanol and CCl4 induced liver damage in rats. The rats were divided into five groups of six animals each and serve as control, toxic, post-treated, herbal control, Liv.52 treated groups respectively. The results showed that the activities of liver marker enzymes in serum namely AST, ALT, ALP, ACP and serum bilirubin level (total) were increased in toxic group animals. But the activities of these enzymes were significantly lowered in post-treated group of rats. Thus, the results suggest antihepatotoxicity of “Ayush-Liv.04”.

Keywords: polyherbal formulation, hepatic damage, CCl4, ethanol, Liv.52, serum enzymes and bilirubin

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