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. 2003 Jan-Mar;22(3):111–114.

ANTIFERTILITY EFFECT OF LINDENBERGIA INDICA (70% EtOH) EXTRACT

Ashok Purohit 1, Surendra K Vyas 1
PMCID: PMC3331010  PMID: 22557096

Abstract

Oral feeding of 70% EtOH extract of Lindenbergia indica to female rats at the dose of 500 mg/kg body weight and 1000 mg / kg body weight caused significant reduction of serum cholesterol, HDL – cholesterol, triglycerides & phospholipids (P≤ 0.05 to P≤ 0.001). Where as the protein levels were not reduced significantly.

Fertility test showed 100% negative results. The negative fertility reflects the arrest of Oogenesis & depletion of estrogen level. Further Lindenbergia indica reflects antiestrogenic nature.

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