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. 2001 Jul-Sep;21(1):12–15.

ANTIHEPATOTOXIC ACTICITY OF COCCINIA INDICA

V Gopalakrishnan 1, KNV Rao 1, M Devi 1, N Padmaha 1, P Manju Lakshmi 1, T Srividya 1, G Vadivukarasi 1
PMCID: PMC3331024  PMID: 22557027

Abstract

Aqueous, light petroleum, chloroform, alcohol, benzene and acetone extracts of the leaves of Coccinia indica. (Family: Cucurbitaceae) were screened for antihepatotoxic activity. The extracts were given after the liver was damaged with Ccl4 Liver function was assessed based on liver to body weight ratio pentobarbitone sleep time, serum levels of transaminase (SGPT, SGOT), alkaline phosphatase (SALP and bilirubin. Alcohol and light petroleum was found to have good anti-hepatotoxic activity.

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