Table 1.
Annual Prescription Volume and Expenditures of Fibrates Overall and by Individual Fibrate
| 2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008 | 2009 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| thousands | Proportion of Total (%) |
thousands | Proportion of Total (%) |
thousands | Proportion of Total (%) |
thousands | Proportion of Total (%) |
thousands | Proportion of Total (%) |
thousands | Proportion of Total (%) |
thousands | Proportion of Total (%) |
thousands | Proportion of Total (%) |
|
| Volume of Prescriptions | ||||||||||||||||
| Canada | ||||||||||||||||
| Bezafibrate | 125 | 7.8% | 129 | 7.5% | 123 | 7.3% | 114 | 6.8% | 106 | 6.2% | 91 | 5.5% | 84 | 4.9% | 78 | 4.6% |
| Fenofibrate | 1,291 | 81.2% | 1,416 | 82.9% | 1,423 | 84.1% | 1,441 | 85.4% | 1,477 | 86.7% | 1,464 | 88.3% | 1,526 | 89.5% | 1,529 | 90.2% |
| Gemfibrozil | 173 | 10.9% | 164 | 9.6% | 146 | 8.6% | 132 | 7.8% | 120 | 7.1% | 103 | 6.2% | 95 | 5.6% | 88 | 5.2% |
| Total | 1,589 | 1,709 | 1,692 | 1,687 | 1,703 | 1,657 | 1,705 | 1,695 | ||||||||
| United States | ||||||||||||||||
| Fenofibrate | 5889 | 47.9% | 7,175 | 52.1% | 8,539 | 56.8% | 10,147 | 62.0% | 11,985 | 66.2% | 13,497 | 69.4% | 15,033 | 71.4% | 15,271 | 65.2% |
| Gemfibrozil | 6407 | 52.1% | 6,586 | 47.9% | 6,494 | 43.2% | 6,225 | 38.0% | 6,120 | 33.8% | 5,960 | 30.6% | 6,034 | 28.6% | 6,121 | 26.1% |
| Fenofibric acid | 0 | 0.0% | 0 | 0.0% | 0 | 0.0% | 0 | 0.0% | 0 | 0.0% | 0 | 0.0% | 0 | 0.0% | 2,031 | 8.7% |
| Total | 12,296 | 13,761 | 15,033 | 16,372 | 18,105 | 19,457 | 21,067 | 23,423 | ||||||||
| Expenditures | ||||||||||||||||
| Canada | ||||||||||||||||
| Bezafibrate | $8,474 | 10.2% | $8,901 | 10.0% | $8,649 | 9.8% | $8,189 | 9.3% | $7,459 | 9.0% | $6,304 | 8.6% | $5,620 | 7.9% | $5,358 | 7.7% |
| Fenofibrate | $66,615 | 79.9% | $71,881 | 81.1% | $72,400 | 82.3% | $73,706 | 83.6% | $70,226 | 84.3% | $62,520 | 85.0% | $61,495 | 86.4% | $60,658 | 86.9% |
| Gemfibrozil | $8,230 | 9.9% | $7,893 | 8.9% | $6,916 | 7.9% | $6,232 | 7.1% | $5,620 | 6.7% | $4,767 | 6.5% | $4,097 | 5.8% | $3,822 | 5.5% |
| Total | $83,323 | $88,675 | $87,966 | $88,127 | $83,306 | $73,590 | $71,212 | $69,839 | ||||||||
| United States | ||||||||||||||||
| Fenofibrate | $398,815 | 64.5% | $557,866 | 70.0% | $735,817 | 75.5% | $894,477 | 80.8% | $1,088,418 | 85.2% | $1,279,653 | 87.4% | $1,471,662 | 88.8% | $1,555,005 | 78.7% |
| Gemfibrozil | $219,670 | 35.5% | $239,526 | 30.0% | $239,193 | 24.5% | $212,776 | 19.2% | $188,818 | 14.8% | $184,348 | 12.6% | $186,456 | 11.2% | $190,989 | 9.7% |
| Fenofibric acid | $0 | 0.0% | $1 | 0.0% | $230,740 | 11.7% | ||||||||||
| Total | $618,493 | $797,392 | $975,010 | $1,107,253 | $1,277,236 | $1,464,001 | $1,658,119 | $1,976,734 | ||||||||
Source: IMS Health-US National Prescription Audit and IS Health-Canada, Canadian CompuScript Audit®.