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. 1991 Jan 25;19(2):303–306. doi: 10.1093/nar/19.2.303

Polymorphisms generated by arbitrarily primed PCR in the mouse: application to strain identification and genetic mapping.

J Welsh 1, C Petersen 1, M McClelland 1
PMCID: PMC333594  PMID: 2014169

Abstract

Polymorphisms in genomic fingerprints generated by arbitrarily primed PCR (AP-PCR) can distinguish between strains of almost any organism. We applied the technique to the mouse (Mus musculus). The characteristic differences in the AP-PCR genomic fingerprints between strains will be of value in strain identification and verification. Using one primer, we genetically mapped four polymorphisms in a set of C57BL/6J x DBA/2J recombinant inbreds. One of these polymorphisms is a length variant. The method will allow rapid genetic mapping of DNA polymorphisms without Southern blotting.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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