Abstract
Amrithadi Churnam – a compound ayurvedic preparation made up of Tinospora cordifolia, Salacia prenoides, Curcuma longa, Tribulus terrestris and Emblica Officinalis was screened for its antidiabetic activity. From the studies it could be established that Amrithadi churnam at a dose level of 100mg/kg b.w. was the optimum dose in alloxan diabetic rats. No toxic effects were observed as evidenced by the study of liver enzymes and blood haematoerit. An extra pancreatic role of the drug cannot be rulled out, since it (100 mg/kg b.w) produced significant decrease in blood sugar level in alloxan diabetic rats.
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