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. 1992 Jul-Dec;12(1-2):264–266.

CONTRACEPTIVE EFFICACY OF SOLANUM XANTHOCARPUM BERRY IN MALE RATS

Ashok Purohit 1
PMCID: PMC3336623  PMID: 22556599

Abstract

Oral feeding of 50% EtOH of Solanum xanthocarpum berry to male rats at the dose of 0.5 gm/kg body weight caused arrest of spermotagenesis. The number of spermatocytes (primary and secondary) and spermatids were significantly reduced (P<0.05 to 0.001). The total number of immature and mature leydig cells were significantly decreased (P<0.001), whereas degenerating cells were significantly increased (P<0.001). The decreased testicular cell population reflects antispermatogenic nature of Solanium xanthocarpum berry extract.

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