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. 1989 Jan-Jun;8(3-4):212–219.

ADAPTOGENIC ACTIVITY OF SEEDS OF TRICHOPUS ZEYLANICUS GAERTN, THE GINSENG OF KERALA

Avinash K Sharma *, P Pushpangadan *, C L Chopra *, S Rajasekharan , L Sarada Amma
PMCID: PMC3336722  PMID: 22557652

Abstract

The alchoholic extract of seeds of Trichopus zeylanicus showed a potent adaptogenic or antistress properties against a variety of stresses in both rats an dmice. The extract increased the swimming performance of normal and adrenalectomized mice. Significantly; prevented a variety of stress and chemical induced ulcerations in rats and also prevented milk-induced leucocytosis in mice. The extract further reduced the gastric secretary clume, PH and acid output in pylorusligated rat stomach. No mortalitiy was observed upto a dose of 3 g/kg per oral in mice. The study indicated that trichopus zeylanicus seeds induce a state of nonspecific increased resistance against a variety of stress induced biological changes in animals.

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