TABLE 2.
Type of Barriers and Inter-rater Agreement on Barriers to Medication Adherencea
| Type | Barrier | κ | 95% CI for κ | Exact P Value |
|---|---|---|---|---|
| Logistical issues | Any logistical issue | 0.44 | (0.29, 0.59) | <.001 |
| Child could not get meds | −0.05 | (–0.19, 0.09) | .70 | |
| Did not refill | 0.14 | (−0.05, 0.33) | .09 | |
| Forgot | 0.41 | (0.25, 0.58) | <.001 | |
| Schedule interfered | 0.10 | (−0.09, 0.30) | .26 | |
| Multiple caregivers | 0.06 | (−0.17, 0.29) | >.99 | |
| Child away | 0.38 | (0.18, 0.58) | <.001 | |
| Busy with other things | 0.19 | (−0.01, 0.39) | .03 | |
| Change in daily routine | 0.15 | (−0.06, 0.35) | .19 | |
| Regimen issues | Any regimen issue | 0.35 | (0.17, 0.53) | <.001 |
| Cannot keep down | 0.44 | (0.21, 0.66) | <.001 | |
| Too much medication | −0.03 | (−0.06, 0.01) | >.99 | |
| Avoid side effects | −0.05 | (−0.08, −0.01) | >.99 | |
| Toxicity | −0.01 | (−0.04, 0.01) | >.99 | |
| Problems taking as directed | 0.12 | (−0.11, 0.36) | .19 | |
| Child Issues | Any child issue | 0.24 | (0.06, 0.42) | .01 |
| Child refused | 0.26 | (0.05, 0.47) | .01 | |
| Child felt sick | 0.08 | (−0.13, 0.29) | .60 | |
| Child felt good | 0.24 | (0.00, 0.48) | .02 | |
| Disclosure issues | Child concerned that others notice medications | 0.19 | (−0.06, 0.44) | .07 |
CI, confidence interval.
a
The barriers, “depression” and “slept through dose time,” were not included in this table because the questions were different for child and caregiver.