Table 3.
Estimated relative hazard of fracture among never users of oral estrogen
| Menopause Type Hazard Ratio (95% CI) |
||
|---|---|---|
| n=4116 | ||
| Surgical | Natural | |
| (n=433) | (n=3683) | |
| Hip | (n fx=46) | (n fx=514) |
| Unadjusted | 0.84 (0.62–1.14) | 1.00 |
| Multivariable | 0.87 (0.63–1.21) | 1.00 |
| Multivariable+Calc BMD | 0.87 (0.63–1.21) | 1.00 |
| Model n=3738 | ||
| Wrist | (n fx=44) | (n fx=360) |
| Unadjusted | 1.14 (0.83–1.56) | 1.00 |
| Multivariable | 1.08 (0.76–1.54) | 1.00 |
| Multivariable+Dist BMD | 1.10 (0.78–1.57) | 1.00 |
| Model n=3703 | ||
| Any non-vertebral | (n fx=175) | (n fx=1444) |
| Unadjusted | 1.17 (1.00–1.37) | 1.00 |
| Multivariable | 1.10 (0.92–1.31) | 1.00 |
| Multivariable+Calc BMD | 1.11 (0.93–1.32) | 1.00 |
| Model n=3461 | ||
Multivariable models adjusted for age, weight, age at menopause, calcium intake (supplement), pack-years smoking, number breastfed, self-reported health status, benzodiazepine use, depth perception, contrast sensitivity