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. 1989 Sep 25;17(18):7273–7281. doi: 10.1093/nar/17.18.7273

DNA duplex with the potential to change handedness after every half a turn.

S K Brahmachari 1, R K Mishra 1, R Bagga 1, N Ramesh 1
PMCID: PMC334807  PMID: 2552407

Abstract

Polymorphic forms of the DNA duplex with long stretches of structural monotony are known. Several alternating purine-pyrimidine sequences have been shown to adopt left-handed Z-conformation. We report a DNA sequence d(CGCGCGATCGAT)n exhibiting alternating right-handed B and left-handed Z helical conformation after every half a turn. Further, this unusual conformation with change in handedness after every six base pairs was induced at physiological superhelical density.

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Selected References

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