Table 2.
Analysis of covariance for difference between memory clinic (MC) and general practitioner (GP) groups for primary and secondary outcome measures at 6 and 12 months’ follow-up
| 6 months’ follow-up | 12 months’ follow-up | ||||||
|---|---|---|---|---|---|---|---|
| Difference (95% CI) between MC and GP* | P value | No | Difference (95% CI) between MC and GP* | P value | No | ||
| Patients’ outcomes | |||||||
| QoL-AD patient, as rated by caregiver† | 0.58 (−0.57 to 1.73) | 0.32 | 153 | 0.49 (−0.66 to 1.63) | 0.40 | 153 | |
| NPI behaviour | 0.63 (−0.81 to 2.06) | 0.39 | 154 | 1.13 (−0.51 to 2.77) | 0.18 | 152 | |
| IDDD help needed | 1.30 (−1.08 to 3.69) | 0.28 | 151 | 0.66 (−1.88 to 3.20) | 0.61 | 148 | |
| IDDD take initiative | 0.44 (−1.38 to 2.26) | 0.64 | 153 | 1.69 (−0.18 to 3.56) | 0.08 | 152 | |
| GDS | −0.03 (−0.56 to 0.50) | 0.91 | 150 | 0.25 (−0.36 to 0.86) | 0.41 | 139 | |
| QoL-AD patient | 0.19 (−0.74 to 1.13) | 0.68 | 153 | 0.25 (−0.76 to 1.23) | 0.62 | 145 | |
| Caregivers’ outcomes | |||||||
| SCQ† | −0.93 (−3.75 to 1.89) | 0.52 | 156 | −2.43 (−5.82 to 0.96) | 0.16 | 153 | |
| QoL-AD caregiver | −0.20 (−1.07 to 0.66) | 0.64 | 154 | 0.17 (−0.70 to 1.04) | 0.70 | 154 | |
| CES D | 0.05 (−2.04 to 2.13) | 0.96 | 153 | 2.09 (0.15 to 4.02) | 0.04 | 151 | |
| ISB | −0.84 (−1.54 to −0.14) | 0.02 | 154 | −0.29 (−0.97 to 0.78) | 0.39 | 151 | |
| NPI emotional | 1.29 (−0.77 to 3.35) | 0.22 | 153 | 1.43 (−0.94 to 3.80) | 0.24 | 152 | |
| EPQ‡ | – | – | – | 0.68 (−0.01 to 1.36) | 0.05 | 151 | |
| STAI trait‡ | – | – | – | 2.14 (0.24 to 4.03) | 0.03 | 152 | |
| STAI state | 3.55 (1.29 to 5.81) | 0.002 | 151 | 2.35 (0.35 to 4.36) | 0.02 | 151 | |
| PMS | −0.03 (−1.17 to 1.10) | 0.95 | 152 | 0.65 (−0.51 to 1.80) | 0.27 | 152 | |
CES D=Center for Epidemiologic Studies depression scale (range 0-60; higher score indicates more depressive); CIRS G=cumulative illness rating scale for geriatrics (range 0-56; higher score indicates more comorbidity); EPQ=Eysenck personality questionnaire, short version, neuroticism (range 0-12; higher score indicates more worried; GDS=geriatric depression scale (range 0-15; higher score indicates more depressive); IDDD=interview for deterioration in daily living activities in dementia (range for “help needed” 0-44; range for “take initiative” 0-36; higher score indicates more help needed or less initiative taken); ISB=inventory for measuring social involvement (range 4-16; higher score indicates more social support); MMSE=mini-mental state examination (range 0-30; higher score indicates better cognition); NPI behaviour=neuropsychiatric inventory in questionnaire format (range 0-36; higher score indicates more behavioural disturbance); NPI emotional= neuropsychiatric inventory in questionnaire format; range 0-60; higher score indicates more emotional problems); PMS=Pearlin mastery scale (range 7-35; higher score indicates less own control; QoL-AD=quality of life in Alzheimer’s disease (range 13-52; higher score indicates better quality of life); SCQ=sense of competence questionnaire (range 27-135; higher score reflects greater sense of competence); STAI=state-trait anxiety inventory (range 20-80; higher score indicates more anxiety.
*Adjusted for type of dementia, severity of dementia, patient’s sex, patient’s age, caregiver’s sex, relationship of patient to caregiver, memory clinic involved, and baseline measurement of relevant outcome.
†Primary outcome measures.
‡Not measured at 6 months’ follow-up.