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. 1967 Sep;58(3):996–1003. doi: 10.1073/pnas.58.3.996

Conformational change and complementarity in the combination of H and L chains of immunoglobulin-G.

K J Dorrington, M H Zarlengo, C Tanford
PMCID: PMC335738  PMID: 4168745

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. COHEN S., PORTER R. B. STRUCTURE AND BIOLOGICAL ACTIVITY OF IMMUNOGLOBULINS. Adv Immunol. 1964;27:287–349. doi: 10.1016/s0065-2776(08)60710-5. [DOI] [PubMed] [Google Scholar]
  2. Cathou R. E., Haber E. Structure of the antibody combining site. I. Hapten stabilization of antibody conformation. Biochemistry. 1967 Feb;6(2):513–518. doi: 10.1021/bi00854a020. [DOI] [PubMed] [Google Scholar]
  3. EDELMAN G. M., OLINS D. E., GALLY J. A., ZINDER N. D. RECONSTITUTION OF IMMUNOLOGIC ACTIVITY BY INTERACTION OF POLYPEPTIDE CHAINS OF ANTIBODIES. Proc Natl Acad Sci U S A. 1963 Oct;50:753–761. doi: 10.1073/pnas.50.4.753. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. FLEISCHMAN J. B., PAIN R. H., PORTER R. R. Reduction of gamma-globulins. Arch Biochem Biophys. 1962 Sep;Suppl 1:174–180. [PubMed] [Google Scholar]
  5. FOUGEREAU M., OLINS D. E., EDELMAN G. M. RECONSTITUTION OF ANTIPHAGE ANTIBODIES FROM L AND H POLYPEPTIDE CHAINS AND THE FORMATION OF INTERSPECIES MOLECULAR HYBRIDS. J Exp Med. 1964 Sep 1;120:349–358. doi: 10.1084/jem.120.3.349. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. FRANEK F., NEZLIN R. S. Recovery of antibody combining activity by interaction of different peptide chains isolated from purified horse antitoxins. Folia Microbiol (Praha) 1963 Mar;8:128–130. doi: 10.1007/BF02877236. [DOI] [PubMed] [Google Scholar]
  7. Fuchs S., Sela M. Preparation and characterization of poly-DL-alanyl rabbit gamma-globulin. J Biol Chem. 1965 Sep;240(9):3558–3567. [PubMed] [Google Scholar]
  8. HOLZWARTH G., DOTY P. THE ULTRAVIOLET CIRCULAR DICHROISM OF POLYPEPTIDES. J Am Chem Soc. 1965 Jan 20;87:218–228. doi: 10.1021/ja01080a015. [DOI] [PubMed] [Google Scholar]
  9. Hill R. L., Delaney R., Fellows R. E., Lebovitz H. E. The evolutionary origins of the immunoglobulins. Proc Natl Acad Sci U S A. 1966 Dec;56(6):1762–1769. doi: 10.1073/pnas.56.6.1762. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Hong R., Nisonoff A. Heterogeneity in the complementation of polypeptide subunits of a purified antibody isolated from an individual rabbit. J Immunol. 1966 Apr;96(4):622–628. [PubMed] [Google Scholar]
  11. Lamm M. E., Nussenzweig V., Benacerraf B. Isolation of purified H and L polypeptide chains from guinea-pig gamma-2-immunoglobulin after mild reduction. Immunology. 1966 Apr;10(4):309–319. [PMC free article] [PubMed] [Google Scholar]
  12. METZGER H., MANNIK M. RECOMBINATION OF ANTIBODY POLYPEPTIDE CHAINS IN THE PRESENCE OF ANTIGEN. J Exp Med. 1964 Nov 1;120:765–782. doi: 10.1084/jem.120.5.765. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Mannik M. Variability in the specific interactions of H and L chains of gamma-G-globulins. Biochemistry. 1967 Jan;6(1):134–142. doi: 10.1021/bi00853a023. [DOI] [PubMed] [Google Scholar]
  14. NOELKEN M. E., NELSON C. A., BUCKLEY C. E., 3rd, TANFORD C. GROSS CONFORMATION OF RABBIT 7 S GAMMA-IMMUNOGLOBULIN AND ITS PAPAIN-CLEAVED FRAGMENTS. J Biol Chem. 1965 Jan;240:218–224. [PubMed] [Google Scholar]
  15. NOSSAL G. J., MAKELA O. Elaboration of antibodies by single cells. Annu Rev Microbiol. 1962;16:53–74. doi: 10.1146/annurev.mi.16.100162.000413. [DOI] [PubMed] [Google Scholar]
  16. OLINS D. E., EDELMAN G. M. RECONSTITUTION OF 7S MOLECULES FROM L AND H POLYPEPTIDE CHAINS OF ANTIBODIES AND GAMMA-GLOBULINS. J Exp Med. 1964 May 1;119:789–815. doi: 10.1084/jem.119.5.789. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. ROHOLT O. A., RADZIMSKI G., PRESSMAN D. POLYPEPTIDE CHAINS OF ANTIBODY: EFFECTIVE BINDING SITES REQUIRE SPECIFICITY IN COMBINATION. Science. 1965 Feb 5;147(3658):613–615. doi: 10.1126/science.147.3658.613. [DOI] [PubMed] [Google Scholar]
  18. ROHOLT O., ONOUE K., PRESSMAN D. SPECIFIC COMBINATION OF H AND L CHAINS OF RABBIT GAMMA-GLOBULINS. Proc Natl Acad Sci U S A. 1964 Feb;51:173–178. doi: 10.1073/pnas.51.2.173. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Rosenberg A. The optical rotatory dispersion of aromatic amino acids and the side chain-dependent Cotton effects in proteins. J Biol Chem. 1966 Nov 10;241(21):5119–5125. [PubMed] [Google Scholar]
  20. Steiner L. A., Lowey S. Optical rotatory dispersion studies of rabbit gamma-G-immunoglobulin and its papain fragments. J Biol Chem. 1966 Jan 10;241(1):231–240. [PubMed] [Google Scholar]
  21. YPHANTIS D. A. EQUILIBRIUM ULTRACENTRIFUGATION OF DILUTE SOLUTIONS. Biochemistry. 1964 Mar;3:297–317. doi: 10.1021/bi00891a003. [DOI] [PubMed] [Google Scholar]

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