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. 1970 Aug;66(4):1127–1135. doi: 10.1073/pnas.66.4.1127

CELLS INVOLVED IN CELL-MEDIATED AND TRANSPLANTATION IMMUNITY, II. A CONSIDERATION OF THE FUNCTIONAL IDENTITY OF THE CELLS INVOLVED IN BOTH HUMORAL AND CELL-MEDIATED IMMUNITY: A PHYLOGENETIC APPROACH

Maxwell Richter 1,*
PMCID: PMC335795  PMID: 4249392

Abstract

The literature concerned with the types of cells that participate in the humoral and cell-mediated immune response has been reviewed. It is postulated that the initial cells that are involved in mediating both types of immunity are functionally identical in that both are antigen-reactive cells. In the case of the humoral immune response, the interaction of the antigen-reactive cells with the antigen leads to the release or transfer of “information” to the antibody-forming cell, resulting in the synthesis and secretion of antibody molecules. In the case of cell-mediated immunity, it is considered that the primitive antigen-reactive cell itself transforms into the sensitized cell which infiltrates the site of antigen administration.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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