Figure 2.
Effect of stress exposure and prior NPS injection into the LA on fear acquisition. (a) Experimental design. NS: non-stressed animals, injection of NPS (NPS_NS) or vehicle (Vehicle_NS) bilaterally into the LA 10 days before fear conditioning. IS-10 D: exposure to IS 10 days before fear conditioning, with injection of NPS (NPS_IS-10D) or vehicle (Vehicle_IS-10D) 20 min before IS. (b) Freezing to the context during a period of 2 min before the first CS+ presentation for session 1 and 2. (c) Freezing to the CS. The data represent the mean of freezing for 6-block CS- and 3-block CS+.