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. 1976 Mar;73(3):928–931. doi: 10.1073/pnas.73.3.928

Influence of polyunsaturated fatty acids on survival of skin allografts and tumor incidence in mice.

J Mertin, R Hunt
PMCID: PMC336033  PMID: 768987

Abstract

Subcutaneous or oral administration of the polyunsaturated fatty acid linoleic acid prolongs survival of skin allografts in mice. Mice fed on a diet deficient in polyunsaturated fatty acids show a relative immunopotentiation, as indicated by accelerated skin allograft rejection and decreased incidence and rate of development of methylcholanthrene-induced tumors. These observations support the hypothesis that polyunsaturated fatty acids take part in immunoregulatory mechanisms.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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