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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1976 Mar;73(3):937–940. doi: 10.1073/pnas.73.3.937

Genetic variation in serum low density lipoproteins and lipid levels in man.

K Berg, C Hames, G Dahlén, M H Frick, I Krishan
PMCID: PMC336035  PMID: 176662

Abstract

Combined data from 10 different populations indicate that the serum cholesterol and triglyceride levels are higher in Ag(x-) than in Ag(x+) individuals. Although the differences were relatively small, they became more pronounced with increasing age. The Ag(x) antigen, which is associated with the serum low density lipoprotein, is genetically controlled and the present study therefore has revealed a small but significant effect of a single autosomal locus on lipids implicated in the pathogenesis of atherosclerosis. No explanation of the higher cholesterol and triglyceride levels in Ag(x-) than in Ag(x+) persons is apparent.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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