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. 2012 May 15;26(10):1122.

MT1-MMP regulates the PI3Kδ•Mi-2/NuRD-dependent control of macrophage immune function

Ryoko Shimizu-Hirota, Wanfen Xiong, B Timothy Baxter, Steven L Kunkel, Ivan Maillard, Xiao-Wei Chen, Farideh Sabeh, Rui Liu, Xiao-Yan Li, Stephen J Weiss
PMCID: PMC3360566

Genes & Development 26: 395–413 (2012)

In this article, the cited references by Cougoule et al. (2010) and Van Goethem et al. (2010) also describe macrophage invasion systems that can operate independently of matrix metalloproteinases. To more accurately reflect those findings, these two sentences should have instead been written as follows:

On page 395, in the righthand column, the sentence that begins the second paragraph should read:

Recent studies suggest that the membrane-anchored metalloproteinase MT1-MMP or other proteolytic systems control macrophage invasion by hydrolyzing ECM components and cell surface molecules as well as activating signal transduction cascades that regulate motility and energy metabolism (Cao et al. 2004; Matias-Roman et al. 2005; Sithu et al. 2007; Barbolina and Stack 2008; D’Alessio et al. 2008; Sakamoto and Seiki 2009, 2010; Cougoule et al. 2010; Gonzalo et al. 2010; Van Goethem et al. 2010).

On page 406, in the lefthand column, the fourth sentence in the Discussion section should read:

Thus, by extension, MT1-MMP as well as other proteolytic systems have been assumed to play similar roles in myeloid cell populations (Sakamoto and Seiki 2009; Cougoule et al. 2010; Van Goethem et al. 2010).


Articles from Genes & Development are provided here courtesy of Cold Spring Harbor Laboratory Press

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