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. 1988 Apr 11;16(7):3005–3012. doi: 10.1093/nar/16.7.3005

v-jun is a transcriptional activator, but not in all cell-lines.

J L Imler 1, E Ugarte 1, C Wasylyk 1, B Wasylyk 1
PMCID: PMC336447  PMID: 2835749

Abstract

The recently isolated v-jun oncogene encodes a protein with sequence homology to the transcription factor AP1, as well as a similar DNA binding specificity. We show, by expressing v-jun in F9 embryocarcinoma cells, that v-jun is also a transcriptional activator. However, v-jun expression does not activate transcription in several other cell-lines, suggesting that cell-specific factors are required for v-jun activity.

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Selected References

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