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letter
. 2012 May 11;109(19):359. doi: 10.3238/arztebl.2012.0359a

Correspondence (letter to the editor): Appeal for Vitamin D Therapy

Stefan Pilz *, Andreas Tomaschitz **, Katharina Kienreich **, Astrid Fahrleitner-Pammer **, Winfried März ***
PMCID: PMC3364530  PMID: 22675407

Stefan Schilling reported that most geriatric patients in a rehabilitation facility had severe vitamin D deficiency (1).

Our observations in women in nursing homes are rather similar (2). Although the optimal 25-hydroxyvitamin D (25[OH]D) concentrations and the potentially multiple health benefits of vitamin D are the subject of intense discussions, the general consensus is that 25(OH)D concentrations below 10 ng/mL (25 mmol/L) affect the skeletal system and require immediate treatment. In view of the fact, however, that 25(OH)D concentrations in most patients in care homes are below 10 ng/mL (25 mmol/L) and meta-analyses of randomized, placebo controlled studies have shown that vitamin D supplementation results in a significant reduction in bone fractures, we wish to point out that existing guidelines actually recommend a daily vitamin D supplementation of 800 IU in such patients.

In agreement with Stefan Schilling we therefore wish to make an appeal for introducing vitamin D supplementation as a routine treatment in care homes. This recommendation is also supported by a meta-analysis of randomized, placebo controlled trials, which shows a significant reduction in mortality as a result of vitamin D supplementation (3).

Although the many questions surrounding vitamin D remain unanswered, and although what we know about vitamin D is likely to be modified in the future, we now carry the responsibility to treat according to the current best evidence, which says very clearly that vitamin D deficiency in the elderly patients described above should be treated.

Footnotes

Conflict of interest statement

Dr Fährleitner-Pammer has received honoraria as well as conference and travel expenses from Amgen, Eli Lilly, Nycomed, Novartis, Roche, MSD, Genzyme, Servier, and Darichi.

The remaining authors declare that no conflict of interest exists.

References

  • 1.Schilling S. Epidemic vitamin D deficiency among patients in an elderly care rehabilitation facility. Dtsch Arztebl Int. 2012;109:33–38. doi: 10.3238/arztebl.2012.0033. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 2.1. Pilz S, Dobnig H, Tomaschitz A, et al. Low 25-hydroxyvitamin D is associated with increased mortality in female nursing home residents. J Clin Endocrinol Metab. 2012;97:653–657. doi: 10.1210/jc.2011-3043. [DOI] [PubMed] [Google Scholar]
  • 3.Bjelakovic G, Gluud LL, Nikolova D, et al. Vitamin D supplementation for prevention of mortality in adults. Cochrane Database Syst Rev. 2011;7 doi: 10.1002/14651858.CD007470.pub2. CD007470. [DOI] [PubMed] [Google Scholar]

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