Table 1.

Percent sequence divergence of SRGAP2 paralogs

	SRGAP2A	SRAGP2B	SRGAP2C	SRGAP2D
SRGAP2A	–	0.015	0.016	0.069
SRAGP2B	0.525	–	0.014	0.038
SRGAP2C	0.584	0.451	–	0.065
SRGAP2D	0.452	0.136	0.400	–

Kimura two-parameter model of genetic distance computed as base substitutions per site (left diagonal) and standard error (right diagonal). Pairwise distances are computed across 244,200 sites representing the complete shared genomic region between SRGAP2 paralogs. Values for SRGAP2D represent pairwise distances computed across 9,541 sites. As a reference, the genetic distance between SRGAP2A and its chimpanzee ortholog locus is 0.852 +/−0.019 while that of chimpanzee to human paralogs SRGAP2B and SRGAP2C (0.901+/−0.019 and 0.960 +/− 0.020) are consistent with the accelerated mutation rate for these chromosomal regions.