Table 1.
Screen at:
|
||
---|---|---|
Age 8 | Age 14 | |
Incremental costs | ||
HCM | $134 | $136 |
WPW | $80 | $79 |
LQTS | $55 | $55 |
Total* | $170 | $171 |
Incremental SCD cases prevented due to: | ||
HCM | 1.1 × 10−5 | 4.7 × 10−5 |
WPW | 2.0 × 10−5 | 2.3 × 10−5 |
LQTS | 5.0 × 10−6 | 5.4 × 10−6 |
Total | 3.6 × 10−5 | 7.5 × 10−5 |
Incremental LYs saved from preventing SCD due to: | ||
HCM | 6.8 × 10−4 | 2.7 × 10−3 |
WPW | 1.1 × 10−3 | 1.2 × 10−3 |
LQTS | 3.4 × 10−4 | 3.9 × 10−4 |
Total | 2.1 × 10−3 | 4.3 × 10−3 |
Incremental discounted LYs saved from preventing SCD due to: | ||
HCM | 2.6 × 10−4 | 1.2 × 10−3 |
WPW | 4.5 × 10−4 | 5.5 × 10−4 |
LQTS | 1.2 × 10−4 | 1.4 × 10−4 |
Total | 8.3 × 10−4 | 1.9 × 10−3 |
Incremental cost per discounted LY from screening for all conditions: | $203,979 | $90,828 |
Abbreviations: HCM, hypertrophic cardiomyopathy; LQTS, long QT syndrome; LY, life year; SCD, sudden cardiac death; WPW, Wolff-Parkinson-White syndrome.
The total has twice the per-individual community-based screening cost subtracted out to avoid triple counting this expense.