Skip to main content
. Author manuscript; available in PMC: 2013 May 29.
Published in final edited form as: Circulation. 2012 May 3;125(21):2621–2629. doi: 10.1161/CIRCULATIONAHA.111.087940

Table 1.

Base Case Results: Incremental Costs and Outcomes per Individual Screened

Screen at:
Age 8 Age 14
Incremental costs
 HCM $134 $136

 WPW $80 $79

 LQTS $55 $55

 Total* $170 $171

Incremental SCD cases prevented due to:
 HCM 1.1 × 10−5 4.7 × 10−5

 WPW 2.0 × 10−5 2.3 × 10−5

 LQTS 5.0 × 10−6 5.4 × 10−6

 Total 3.6 × 10−5 7.5 × 10−5

Incremental LYs saved from preventing SCD due to:
 HCM 6.8 × 10−4 2.7 × 10−3

 WPW 1.1 × 10−3 1.2 × 10−3

 LQTS 3.4 × 10−4 3.9 × 10−4

 Total 2.1 × 10−3 4.3 × 10−3

Incremental discounted LYs saved from preventing SCD due to:
 HCM 2.6 × 10−4 1.2 × 10−3

 WPW 4.5 × 10−4 5.5 × 10−4

 LQTS 1.2 × 10−4 1.4 × 10−4

 Total 8.3 × 10−4 1.9 × 10−3

Incremental cost per discounted LY from screening for all conditions: $203,979 $90,828

Abbreviations: HCM, hypertrophic cardiomyopathy; LQTS, long QT syndrome; LY, life year; SCD, sudden cardiac death; WPW, Wolff-Parkinson-White syndrome.

*

The total has twice the per-individual community-based screening cost subtracted out to avoid triple counting this expense.