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. 1988 May 25;16(10):4607–4620. doi: 10.1093/nar/16.10.4607

Synthesis of cyclic oligonucleotides by a modified phosphotriester approach.

E de Vroom 1, H J Broxterman 1, L A Sliedregt 1, G A van der Marel 1, J H van Boom 1
PMCID: PMC336652  PMID: 3380690

Abstract

Evidence will be presented to show that the allyl group is suitable for the protection of a 3'-terminal phosphodiester function. The latter will be demonstrated by the synthesis, via a phosphotriester approach, of two cyclic tetraribonucleotides [r(AAAA) and r(UAMe2UAMe2)], two cyclic hexadeoxyribonucleotides [d(CGCGCG) and d(TAAAAA)] and a cyclic octadeoxyribonucleotide [d(CGTGCGTG)].

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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