Table 1.
Demographic characteristics of study group
| PS1 mutation carriers, n = 30 | PS1 mutation noncarriers, n = 21 | p | |
|---|---|---|---|
| Absolute age, y | 28.9 (18–47) | 29.3 (18–43) | 0.87 |
| Relative age, y before median age at AD diagnosis in family | 14.9 (1–25) | 15.1 (0–30) | 0.93 |
| Sex, % F | 60 (n = 18) | 76 (n = 16) | χ2, 0.23 |
| Education, y | 11.1 (6–17) | 12.7 (7–18) | 0.06 |
| Type of mutation in family (A431E vs L235V) | 83% A431E (n = 25) | 71% A431E (n = 15) | χ2, 0.31 |
| 27% L235V (n = 5) | 29% L235V (n = 6) | ||
| Beck Depression Inventory score | 11.4 (0–42) | 7.9 (0–35) | 0.21 |
Numbers or ranges are shown in parentheses.
AD = Alzheimer disease.