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Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology logoLink to Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology
. 2010 Nov 4;6(Suppl 2):P6. doi: 10.1186/1710-1492-6-S2-P6

Flax seed allergy in children: an emerging allergen?

Andrew O’Keefe 1,, Sandeep Kapur 2, Gregory Rex 2, Wade Watson 2
PMCID: PMC3374192

Background

Flax is a plant that is widely cultivated and has multiple uses. The seed has been increasingly used in food, and the fibers are used in textiles. Oils have also been extracted from the seed for use as a laxative and in industrial preparations. Allergic reactions to flax seed ingestion as well as linseed oil (flaxseed oil) ingestion have been described in the literature in adults (1-5), but not in children.

Material and methods

We report four cases of flax seed allergy in children.

Results

See table 1

Table 1.

Case Age Gender Multiple food allergies? Food containing flax seed: symptoms Skin test to flax Open challenge
1 1y5m F no granola bar: urticaria, angioedema 5mm not done
2 9y M yes muffin: oral “tingling” 4mm oral pruritus, throat clearing
3 5y M yes bread: vomiting/urticaria (two episodes) 7mm not done
4 8y M yes fruit smoothie: angioedema of lips
same fruit smoothie without flax seed before and since: no symptoms
pending pending

Conclusions

Few cases of flax seed allergy have been described in the literature. As the use of flax seed in foods becomes more prevalent, this will likely become a more important cause of allergic reactions in the future.

References

  1. Alonso L, Navarro JA, Garces M, Carretero P. Anaphylaxis caused by linseed (flaxseed) intake. Journal of Allergy and Clinical Immunology. 1996;98(2):469–470. doi: 10.1016/S0091-6749(96)70175-6. [DOI] [PubMed] [Google Scholar]
  2. Black WC. Flax hypersensitiveness. JAMA. 1930;94:1064. [Google Scholar]
  3. Grant LR. A report of six cases of flax seed sensitization with review of the literature. The Journal of Allergy. 1931;3:469–477. doi: 10.1016/S0021-8707(32)90182-8. [DOI] [Google Scholar]
  4. Lezaun A. et al. Anaphylaxis from linseed. Allergy. 1998;53:105–106. doi: 10.1111/j.1398-9995.1998.tb03785.x. [DOI] [PubMed] [Google Scholar]
  5. Leon F, Rodriguez M, Cuevas M. The major allergen of linseed. Allergy. 2002;57(10):968. doi: 10.1034/j.1398-9995.2002.23832_14.x. [DOI] [PubMed] [Google Scholar]

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