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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Pain. 2011 Jul 22;152(10):2323–2332. doi: 10.1016/j.pain.2011.06.025

Table 3.

EDNRB PCR Product CpG Site Mean Methylation Difference p-value of Student t test
EDNRB 1 CpG 4 0.15 <.0001
CpG 5 0.24 <.0001
CpG 6–7 0.30 <.0001
CpG 8–9 0.29 <.0001
CpG 10–11–12 0.29 <.0001
CpG 13 0.24 <.0001
CpG 14–15 0.27 <.0001
CpG 16 0.17 <.0001
CpG 17–18 0.20 <.0001
CpG 19 0.30 <.0001
EDNRB 2 CpG 1–2 0.22 <.0001
CpG 3–4 0.51 <.0001
CpG 5 0.32 <.0001
CpG 8 0.34 <.0001
CpG 9–10 0.19 .0001
CpG 13–14–15 0.36 <.0001
CpG 16 0.32 <.0001
CpG 17 0.51 <.0001
CpG 18–19 0.55 <.0001
CpG 20 0.36 <.0001
CpG 21 0.56 <.0001
CpG 22–23 0.43 <.0001
CpG 24 0.36 <.0001
CpG 25 0.39 <.0001
CpG 26 0.39 <.0001
EDNRB 3 CpG 1 0.23 .0001
CpG 2–3–4 0.27 <.0001
CpG 5 0.21 <.0001
CpG 6–7 0.37 <.0001
CpG 8 0.32 <.0001
CpG 9 0.26 <.0001
CpG 10–11 0.33 <.0001
CpG 12 0.28 <.0001
CpG 14 0.14 .0002
CpG 15 0.26 <.0001
CpG 16 0.26 <.0001
CpG 18 0.19 <.0001
CpG 19 0.22 <.0001
CpG 20 0.32 <.0001
CpG 27 0.19 <.0001
CpG 28 0.31 <.0001
EDNRB 4 CpG 1 −0.03 .4728
CpG 2–3 0.02 .3934
CpG 4 0.10 .0557
CpG 6 0.16 .0011
CpG 7 0.08 .0084
CpG 8 0.10 .0082
CpG 9–10 0.27 <.0001
CpG 12 0.32 <.0001
CpG 14–15 0.26 <.0001
CpG 16 0.20 .0003