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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Neuropharmacology. 2012 Apr 26;63(3):434–440. doi: 10.1016/j.neuropharm.2012.04.015

Figure 5. Nicotinic α3β4 receptor blockade in the MHb does not affect increases in accumbal dopamine elicited by acute administration of other drugs of abuse.

Figure 5

A: Rats (n = 4 per group) were given an intra-habenular injection of AuIB or vehicle 20 min prior to an acute i.p, injection of d-amphetamine (1 mg/kg). d-amphetamine administration caused a robust increase in extracellular dopamine in the NAcc; this was not attenuated by AuIB pretreatment. B: 18-MC did not have an effect on extracellular dopamine levels in the NAcc following an acute injection of morphine (5 mg/kg., i.p.; 18-MC data were re-plotted from Fig. 7 of Taraschenko et al., 2007; n = 5–7 per group).