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. Author manuscript; available in PMC: 2013 Aug 16.
Published in final edited form as: Neuroscience. 2012 Apr 30;217:56–66. doi: 10.1016/j.neuroscience.2012.04.054

Figure 1. Modulation of Kv2.1 by NMDAR does not depend on the identity of the NR2 subunit.

Figure 1

A. Representative whole-cell currents from an HEK293 cell expressing GFP-Kv2.1 plus NR2a-containing NMDAR either before (-glut) or at the indicated time after the addition of 10 μM glutamate to the extracellular solution. Scale bars: 50 ms, 1 nA. B. Average normalized tail current-voltage (I-V) relationship for the timepoints described in A. C. Average V1/2 for all timepoints following glutamate addition. *, p < 0.001. D. Representative whole-cell recordings from HEK293 cell expressing GFP-Kv2.1 plus NR2b-containing NMDAR. Conditions are the same as in A. E. Average normalized tail I-V relationships for all timepoints. F. Average V1/2 for all timepoints after glutamate addition, *, p < 0.001.