TABLE 4.
Impact of Internalizing Versus Externalizing Psychiatric Disorders on HRQoL in CWE
| Externalizing Psychiatric Disorders, β (95% CI) | Internalizing Psychiatric Disorders, β (95% CI) | |
|---|---|---|
| Child report (CHQ-CF87) | ||
| Physical function | 3.6 (−0.2 to 7.4) | −10.3 (−15.2 to −5.5)a |
| Role/social limitations–physical | −6.0 (−10.6 to −1.5) | −4.5 (−10.3 to 1.3) |
| Role/social limitations–behavioral | −3.5 (−8.5 to 1.5) | −8.5 (−14.9 to −2.1)a |
| Role/social limitations–emotional | −1.2 (−6.6 to 4.3) | −10.3 (−17.2 to −3.4)a |
| Mental health | −1.2 (−5.9 to 3.6) | −13.0 (−19.1 to −7.0)a |
| Self-esteem | −0.9 (−5.3 to 3.4) | −12.6 (−18.2 to −7.1)a |
| Behavior | −4.0 (−8.2 to 0.3) | −8.7 (−14.1 to −3.3) |
| Bodily pain/discomfort | 0.8 (−5.3 to 6.9) | −14.6 (−22.4 to −6.8)a |
| General health perceptions | −2.5 (−7.2 to 2.2) | −14.2 (−20.1 to −8.2)a |
| Family activities | −4.7 (−11.7 to 2.4) | −14.3 (−23.3 to −5.3)a |
| Family cohesion | −1.4 (−9.3 to 6.5) | −13.4 (−23.5 to −3.4)a |
| Global behavior | −11.0 (−17.2 to −4.9)a | −5.0 (−12.8 to 2.9) |
| Global general health | −3.8 (−9.6 to 2.1) | −11.5 (−18.9 to −4.0)a |
| Parent report (CHQ-PF50) | ||
| Physical function | 0.5 (−3.9 to 4.8) | −5.3 (−10.9 to 0.3) |
| Role/social limitations–physical | 1.2 (−4.4 to 6.9) | −4.8 (−12.0 to 2.4) |
| Role/social limitations–emotional/behavioral | −4.6 (−12.3 to 3.0) | −31.5 (−41.2 to −21.8)a |
| Mental health | −3.6 (−7.8 to 0.7) | −26.6 (−32.0 to −21.2)a |
| Self-esteem | 1.6 (−4.0 to 7.2) | −25.6 (−32.8 to −18.5)a |
| Behavior | −11.9 (−16.9 to −6.9)a | −21.2 (−27.6 to −14.8)a |
| Bodily pain/discomfort | 7.9 (1.6 to 14.2) | −13.0 (−21.0 to −5.0) |
| General health perceptions | −2.3 (−7.2 to 2.6) | −4.4 (−10.7 to 1.9) |
| Family activities | −10.4 (−16.6 to −4.2)a | −29.1 (−36.9 to −21.2)a |
| Family cohesion | −4.7 (−11.6 to 2.2) | −14.6 (−23.4 to −5.8) |
| Global behavior | −13.3 (−20.1 to −6.6)a | −31.4 (−40.1 to −22.8)a |
| Global general health | 3.0 (−2.1 to 8.0) | −12.0 (−18.4 to −5.7)a |
| Parent impact on time | −0.1 (−6.3 to 6.0) | −29.8 (−37.7 to −22.0)a |
| Parent emotional impact | −6.0 (−12.9 to 0.9) | −21.1 (−29.9 to −12.3)a |
| Summary (T) scores | ||
| Physical summary score | 1.9 (−0.5 to 4.3) | −1.7 (−4.8 to 1.4) |
| Psychosocial summary score | −3.7 (−6.6 to −0.8)a | −18.8 (−22.6 to −15.1)a |
N = 277 child-parent dyads. Age- and gender-adjusted multiple linear regression models. Dependent variables included each respective CHQ-CF87 and CHQ-PF50 scale, item, or summary score, in separate regression models. Independent variables for all models included dichotomous indicators of internalizing and externalizing psychiatric disorders (coefficients shown above), in addition to dichotomous indicators for NDSD, chronic medical conditions, migraine, complicated epilepsy, and 5-year seizure-free status. Internalizing and externalizing psychiatric disorders were not mutually exclusive. Of those children with any psychiatric disorder (n = 71), 39.4% (n = 28) had an internalizing disorder, 81.7% (n = 58) had an externalizing disorder, and 21% (n = 15) had both at least 1 internalizing and externalizing disorder. CI indicates confidence interval.
P ≤ .0125.