Table 3.

Quantitative analysis of vessel calcification by μCT and corresponding bone morphogenetic protein-2 (BMP-2) expression by Western blot analysis.

	Mineral Density (mg/cm3)	Particle Density (particles/cm3)	Calcific Arc Angle	BMP-2 (Arbitrary Units)
OVX (n=12)	8.4 ± 2.8	94 ± 26	33 ± 7°	37.7 ± 0.1
Low RLX (n=12)	6.4 ± 2.1	89 ± 27	67 ± 10° *	62.5 ± 0.1
High RLX (n=12)	5.8 ± 2.0	79 ± 23	60 ± 11°	53.9 ± 0.1
All RLX (n=12)	6.1 ± 1.4	85 ± 17	63 ± 7° †	58.2 ± 0.1 *

All values expressed as mean ± SEM;

^*p<0.05 and

^†p<0.01 versus OVX.

OVX: ovariectomized control group; RLX: raloxifene therapy group (Low: low-dose, High: high-dose).