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. 1988 Nov 11;16(21):10153–10169. doi: 10.1093/nar/16.21.10153

The yeast ADR6 gene encodes homopolymeric amino acid sequences and a potential metal-binding domain.

P J O'Hara 1, H Horowitz 1, G Eichinger 1, E T Young 1
PMCID: PMC338843  PMID: 3143101

Abstract

The ADR6 gene of Saccharomyces cerevisiae has an open reading frame which could encode a polypeptide of 1314 amino acids. The predicted mRNA encodes a protein with homopolymeric stretches of asparagine and threonine, particularly near its amino terminus and contains additional sequences consisting of polyglutamine repeats. The predicted protein also contains a potential metal binding (Cys)4-type finger near its carboxy-terminus. An ADR6/beta-galactosidase fusion protein was predominantly nuclear in location, consistent with its role as an activator of ADH2 transcription.

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Selected References

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