Table 1.
Trait | All | Phase 1 | Phase 2 | p value |
---|---|---|---|---|
Families (n) | 140 | 67 | 73 | |
Participants (n) | 513 | 227 | 286 | |
Male sex (%) | 41.9 | 41.4 | 42.4 | 0.85 |
Age (years) | 32.7±10.9 | 29.7±8.7 | 35.1±11.9 | <0.0001 |
BMI (kg/m2) | 28.5±5.9 | 28.2±5.9 | 28.8±6.0 | 0.27 |
Diabetes (%) | 7.7 | 6.8 | 8.9 | 0.36 |
Fasting insulin (pmol/l) | 90.6±59.4 | 94.8±57.1 | 87.0±61.2 | 0.16 |
Fasting glucose (mmol/l) | 5.31±0.46 | 5.33±0.47 | 5.30±0.44 | 0.41 |
HOMA-IR | 3.9±3.4 | 4.2±3.6 | 3.6±3.3 | 0.03 |
HOMA-%B | 184.6±134.2 | 212.1±150.4 | 160.8±113.4 | <0.0001 |
M value (μmol m−2 min−1) | 1,308.8±575.0 | 1,306.6±593.9 | 1,310.5±561.2 | 0.94 |
SSPI (pmol/l) | 832.2±197.4 | 814.8±201.6 | 830.2±193.8 | 0.41 |
Unless otherwise stated, values are mean ± SD