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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Transfusion. 2012 Mar 27;52(12):2533–2550. doi: 10.1111/j.1537-2995.2012.03618.x

Figure 1. Proteins with early elevation following trauma.

Figure 1

Blood samples were collected from trauma patients beginning with arrival to the ER and up to 1 year after injury. Multiplexing techniques were used to measure the levels of 41 immunomodulatory proteins in the plasma. Multivariable GEE models were generated using the natural log of the concentration of each protein as the dependent variable and time since trauma, ISS, injury type, size of transfusion, age, sex, and microchimerism as the independent variables. Concentration of proteins with a statistically significant change in concentration over time since trauma (p<0.05) are plotted in black (raw data) with the model’s prediction of the influence of time since trauma on concentration (controlling for all other independent variables) overlaid in red. **p<0.01, ***p<0.001.