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. 1986 Jan 10;14(1):381–387. doi: 10.1093/nar/14.1.381

Computer graphics program to reveal the dependence of the gross three-dimensional structure of the B-DNA double helix on primary structure.

C S Tung, S C Harvey
PMCID: PMC339421  PMID: 3753773

Abstract

Programs are presented to plot the gross three-dimensional structure of the DNA double helix with the base sequence as input information. The rules that determine the overall structure of the double helix are those that predict the dependence of local helix parameters (specifically, helix twist angle and relative basepair roll angle) on sequence. For this purpose, the user can select either the Calladine-Dickerson parameters or the Tung-Harvey parameters. These programs can be used as tools to investigate the variation of DNA tertiary structure with sequence, which may play an important role in the sequence-specific recognition of DNA by proteins.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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