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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: Shock. 2012 Aug;38(2):170–176. doi: 10.1097/SHK.0b013e31825b2db3

Figure 2. Post-irradiation increase in intestinal permeability and time course of PCT levels.

Figure 2

  • C)
    Intestinal permeability was measured in vivo, 4 days after sham-irradiation or exposure to 9, 10, or 12 Gy total body irradiation (TBI).
    • Compared to sham-irradiated mice, the increase in permeability was highly statistically significant both after 10 Gy (p=0.01) and after 12 Gy (p=0.004).
    • Mean ± SEM, 4–5 mice per group.
  • D)
    Plasma procalcitonin (PCT) levels were measured by a specific ELISA assay at baseline and 4, 6, 8, or 10 days after TBI (9 Gy or 10 Gy).
    • The increase in plasma PCT was highly time-dependent (p<10−6) and radiation dose dependent (p=0.002).
    • Mean ± SEM, 6 mice per group.