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. 2012 Apr 29;67(8):718–726. doi: 10.1136/thoraxjnl-2011-201445

Table 4.

The proportion of people in excess of thresholds for overall cohort, for subgroups of normal, GOLD stage 1, GOLD stage 2 and GOLD stage 3–4

Variables Overall Normal GOLD stage 1 GOLD stage 2 GOLD stage 3–4
FEV1-based thresholds N1=10 217 N1=7931 N1=846 N1=790 N1=219
 ΔFEV1 (>284 ml) 6.7% 5.6% 11.5% 12.2% 7.3%
 ΔFEV1i (>12%) 7.8% 4.4% 11.6% 27.3% 43.4%
 ΔFEV1p (>10%) 6.0% 4.3% 12.3% 13.9% 9.1%
FVC-based thresholds N2=9546 N2=7697 N2=819 N2=764 N2=212
 ΔFVC (>322 ml) 7.5% 4.0% 21.2% 20.7% 29.7%
 ΔFVCi (>10.5%) 7.5% 3.8% 17.0% 24.7% 42.5%
 ΔFVCp (>9.2%) 6.8% 3.2% 21.6% 20.5% 27.8%

ΔFEV1 (ml) and ΔFVC (ml) are absolute change after bronchodilator; ΔFEV1i and ΔFVCi are change as a per cent of initial value; ΔFEV1p and ΔFVCp are change as per cent of predicted value. N1 is number with non-missing FEV1 values and N2 is number with non-missing FVC values.

Normal = not classified as any GOLD stage; GOLD stage 1 = FEV1/FVC <0.7 and FEV1 % predicted >80%; GOLD stage 2 = FEV1/FVC <0.7 and FEV1 % predicted <80% and >50%; GOLD stage 3–4 = FEV1/FVC <0.7 and FEV1 % predicted <50%.

COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; GOLD, Global Initiative for Chronic Obstructive Lung Disease.