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. 1987 Mar 11;15(5):2295–2307. doi: 10.1093/nar/15.5.2295

Correlation of the physical and genetic maps in the lin-12 region of Caenorhabditis elegans.

I Greenwald, A Coulson, J Sulston, J Priess
PMCID: PMC340635  PMID: 2882468

Abstract

We describe the assembly of a set of overlapping clones from the lin-12 III chromosomal region that spans approximately 600 kb, and the identification of two restriction fragment length polymorphisms, eP6 and eP7, that flank the lin-12 locus. A comparison of the physical map and the genetic map yields approximate measurements of 930 kb/map unit for the eP6--lin-12 interval and 830 kb/map unit for the lin-12--eP7 interval. We interpret these values as supporting the proposal that the apparent clustering of genes observed for C. elegans autosomes results from decreased recombination frequency in clusters and not from nonrandom distribution of genes on the physical map.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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