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. 1987 Apr 10;15(7):2911–2926. doi: 10.1093/nar/15.7.2911

Rapid hybridization kinetics of DNA attached to submicron latex particles.

S F Wolf, L Haines, J Fisch, J N Kremsky, J P Dougherty, K Jacobs
PMCID: PMC340706  PMID: 2951654

Abstract

We describe a novel method for attaching any DNA molecule to submicron latex beads and characterize the hybridization kinetic properties of these bead-DNA conjugates. The conjugates hybridize to DNA in solution with rates comparable to homogeneous hybridization reactions, are compatible with common hybridization conditions and are conveniently manipulated. They should thus serve as useful reagents for the fractionation and characterization of DNA and RNA.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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