Skip to main content
. Author manuscript; available in PMC: 2012 Aug 2.
Published in final edited form as: Cell. 2012 Mar 16;148(6):1099–1109. doi: 10.1016/j.cell.2012.02.023

Figure 1. New Tools in Mammalian Disease Models.

Figure 1

Platforms for the genetic manipulation of mammalian model systems (primarily mouse, rat, and human) have developed at an incredible rate in the past 10–15 years. Recent sophisticated adaptations in each of these systems (indicated in yellow) now provide an extremely flexible array of tools for investigating and understanding the underlying causes of human disease.