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. 1985 Mar 11;13(5):1703–1716. doi: 10.1093/nar/13.5.1703

Characterization of a mitochondrial protein binding to single-stranded DNA.

B Mignotte, M Barat, J C Mounolou
PMCID: PMC341106  PMID: 4039816

Abstract

A DNA-binding protein from Xenopus laevis oocyte mitochondria which has been found associated with the D-loop also shows a strong preference for single-stranded DNA. The binding to polynucleotides is dependent on the base composition, but no sequence specificity was found. This protein, called mtSSB, binds tightly and cooperatively to single-stranded DNA. By its amino-acid composition and its binding properties it appears to be similar to the single-stranded DNA-binding proteins found in prokaryotes.

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Selected References

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