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. 1985 Mar 25;13(6):1965–1975. doi: 10.1093/nar/13.6.1965

Organization of Plasmodium falciparum genome: 1. Evidence for a highly repeated DNA sequence.

R V Guntaka, S Gowda, A S Rao, T J Green
PMCID: PMC341128  PMID: 4000949

Abstract

Plasmodium falciparum DNA, isolated from the merozoite stage, was cleaved with HindIII and cloned in pBR322 and lambda L47.1 vectors. Plasmid clones containing 13.4, 7.0, 4.3, 4.1 and 1.5 kb inserts were characterized in some detail. The inserts contain several repeating units of smaller size. Nucleic acid hybridization studies showed that the repeat element is present in the Plasmodium DNA at a very high copy number and appears to be distributed widely throughout the genome.

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Selected References

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