Table 2 . ATPase activities of dynein isolated from wild-type and AAA3 E/Q strains.

Dynein	Basal ATPase (nmol/min/mg dynein)	MT-stimulated ATPase (nmol/min/mg dynein)	Fold change
Wild type	115 ± 7	201 ± 3	∼1.7
AAA3 E/Q	418 ± 35	729 ± 60	∼1.7

Basal and microtubule-stimulated ATPase activities are expressed as mean ± SD derived from three independent experiments. The basal and microtubule-stimulated ATPase rates are significantly different from each other in both wild-type and AAA3 E/Q dynein (t-test, P < 0.05).