Table 5. Correlation Between Spatial and Temporal Changes in the Growth Plate.
Correlation between temporal and spatial regulation of gene expression in the growth plate cartilage. The top 200 genes (P < 0.01, ranked by geometric fold change) that changed significantly either with age, resting to proliferative zone, or proliferative to hypertrophic were analyzed. Changes in mRNA levels were compared by correlation analysis. The correlation coefficients (r values) and P values were shown.
Top 200 genes changing from 3 wk to 12 wk | ||
Comparison between: | Pearson’s r value | P value |
3 to 12wk vs RZ to PZ | 0.0160 | 0.8226 |
3 to 12wk vs PZ to HZ | 0.1561 | 0.0273 |
Top 200 genes changing from resting to proliferative zone: | ||
Comparison between: | Pearson’s r value | P value |
RZ to PZ vs 3 to 12wk | −0.1411 | 0.0462 |
Top 200 genes changing from proliferative to hypertrophic zone: | ||
Comparison between: | Pearson’s r value | P value |
PZ to HZ vs 3 to 12wk | 0.1999 | 0.0045 |