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. 1978 Apr;5(4):1371–1380. doi: 10.1093/nar/5.4.1371

The helical model of the nucleosome core.

E Trifonov
PMCID: PMC342084  PMID: 652526

Abstract

A model of the nucleosome core is proposed based on a topologically linear array of histones attached sequentially to DNA. The linear complex folds helically forming a spring-like particle. Different variants of the particle are discussed (cylindrical springs with and without histone-histone contacts between turns of the helix, solenoidal spring). The model is consistent with known data about the nucleosome structure. Histones H3 and H4 have a special role in the model which is related also to the superstructure of chromatin.

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Selected References

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